"Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired. Since prednisone is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of cortical."
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"Prednisone may interact with estrogens and phenytoin. Prednisone and Prednisolone are members of the glucocorticoid class of hormones. Prednisone is the most commonly-prescribed oral corticosteroid. Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired."