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Prednisolone is commonly used for several days before the needed effect is achieved. Prednisone is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of cortical. Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired. Prednisolone is a corticosteroid medicine. Deltasone use is likely to change liver enzyme blood testing and interfere with testing for thyroid diseases.
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