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Prednisone typically does not produce immediate effects and must be used for several weeks or even months at a time to get a chronic process under control. Prednisone may interact with estrogens and phenytoin. Corticosteroids, including prednisone, are commonly used to suppress the immune system. Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired. In the morning to mimic the natural production of corticosteroids by the body.
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