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Hydrochlorothiazide may cause you to become sunburned more easily. Although there are no adequate and well-controlled studies using hydrochlorothiazide in pregnancy, thiazide diuretics may cause an increased risk of congenital defects. Hydrochlorothiazide reduces the swelling and water retention caused by various medical conditions, such as heart, liver, or kidney disease. Hydrochlorothiazide has an additive effect on lowering blood pressure. Hydrochlorothiazide may increase the blood level of the medicine lithium, and this medicine is therefore not recommended for people taking lithium.
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